The 2022 Colorado Ayurveda Conference took place October 8-9 at the Millennium Harvest House Hotel in beautiful Boulder, Colorado. The theme of Manas: Integrative Approaches to Mental Health brought together a diverse collection of speakers and experts with a wide variety of experience. The resurgence of research into the efficacy of psychedelic-assisted therapy was a major focus. The conference represented a convergence of ancient and modern approaches to entheogenic medicine, as well as a wealth of support for mental health maintenance and enhancement. The complete recordings of the conference are now available for public benefit and NAMA PACE credits.